The Biophysical Browser now has the option to annotate only differential protein-DNA or protein-RNA binding due to annotated SNPs, methylated DNA, or methylated RNA. With this menu option to annotate only differential binding, users can now search for likely functional SNPs within annotated binding sites or possibly functional binding sites that overlap annotated, functional SNPs. With this new functionality, the ADB is a unique resource for searching for functional SNPs and binding sites that drive the differences in gene expression observed in high-throughput transcriptome and proteome data.

CONTACT

Dr. Todd Riley
Assistant Professor of Biology
University of Massachusetts Boston
100 Morrissey Blvd. | ISC Building Room 4730
Boston, Massachusetts 02125
Phone: (617) 287-3236

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